Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is a Vietnamese traditionally medicinal plant utilized in the management of numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This study aimed to research the consequences of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The outcome indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the highest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (with the exception of total flavonoids) and antioxidant capacity, when compared with conventional and ultrasound-assisted extractions. These data show that the use of methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application in the nutraceutical and/or pharmaceutical industries.

Drying methods, solvents and extraction methods greatly affect the phytochemical compounds and biological activity from plant materials. The aims of the study were to determine the consequences of various drying methods, various solvents and extraction methods on the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root extracted from Vietnam. The final results showed that microwave drying was a highly effective method in removal of water in terms of shortest drying time, lowest energy consumption as well as retention of phytochemical compounds and antioxidant capacity in the P. trimera root while methanol and microwave-assisted extraction were the top solvent and means for greatest extraction with the phytochemical compounds and antioxidant capacity from the P. trimera root. The findings because of this study allow retaining the very best amounts of phytochemical compounds and antioxidant capacity from the P. trimera root for potential application within the nutraceutical industry.

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