Xao tam phan (Paramignya trimera (Oliv.) Guillaum) can be a Vietnamese traditionally medicinal plant used in the management of numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This study aimed to analyze the effects of 5 various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The final results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the maximum antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (except for total flavonoids) and antioxidant capacity, when compared with conventional and ultrasound-assisted extractions. These data demonstrate that using methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application inside the nutraceutical and/or pharmaceutical industries.

Drying methods, solvents and extraction methods greatly get a new phytochemical compounds and biological activity from plant materials. The aims of the study would determine the effects of different drying methods, various solvents and extraction methods around the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root from Vietnam. The outcomes established that microwave drying was a powerful method in removing water with regards to shortest drying time, lowest energy consumption as well as retention of phytochemical compounds and antioxidant capacity through the P. trimera root while methanol and microwave-assisted extraction were the best solvent and method for greatest extraction in the phytochemical compounds and antioxidant capacity through the P. trimera root. The findings out of this study allow retaining the very best amounts of phytochemical compounds and antioxidant capacity through the P. trimera root for potential application inside the nutraceutical industry.

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